'The Large Turf' a watercolour by Albrecht Dürer, 1503. Ostensibly a study for larger-themed works, the image has come to represent humanism. An interesting article by Tom Lubbock discusses the paradoxical moment where this image- celebrated for the manner by which it depicts plants embedded in the nature- stops, has an edge and sits on blank paper as a fragment, a specimen.
A Young Hare, 1502. I'm starting with these pictures because of their intensity. Everything is Something.
As Georges Perec said: "Note down what you can see. Anything worthy of note going on. Do you know how to see what's worthy of note? Is there anything that strikes you? Nothing strikes you. You don't know how to see."